Nature Communications (Dec 2021)
Atlas of RNA editing events affecting protein expression in aged and Alzheimer’s disease human brain tissue
- Yiyi Ma,
- Eric B. Dammer,
- Daniel Felsky,
- Duc M. Duong,
- Hans-Ulrich Klein,
- Charles C. White,
- Maotian Zhou,
- Benjamin A. Logsdon,
- Cristin McCabe,
- Jishu Xu,
- Minghui Wang,
- Thomas S. Wingo,
- James J. Lah,
- Bin Zhang,
- Julie Schneider,
- Mariet Allen,
- Xue Wang,
- Nilüfer Ertekin-Taner,
- Nicholas T. Seyfried,
- Allan I. Levey,
- David A. Bennett,
- Philip L. De Jager
Affiliations
- Yiyi Ma
- Center for Translational & Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center
- Eric B. Dammer
- Department of Biochemistry, Emory University School of Medicine
- Daniel Felsky
- Krembil Centre for Neuroinformatics, Centre for Addiction and Mental Health
- Duc M. Duong
- Department of Biochemistry, Emory University School of Medicine
- Hans-Ulrich Klein
- Center for Translational & Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center
- Charles C. White
- Cell Circuits Program, Broad Institute
- Maotian Zhou
- Department of Biochemistry, Emory University School of Medicine
- Benjamin A. Logsdon
- Sage Bionetworks
- Cristin McCabe
- Cell Circuits Program, Broad Institute
- Jishu Xu
- Rush Alzheimer’s Disease Center, Department of Neurological Sciences, Rush University Medical Center
- Minghui Wang
- Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place
- Thomas S. Wingo
- Department of Neurology, Emory University School of Medicine
- James J. Lah
- Department of Neurology, Emory University School of Medicine
- Bin Zhang
- Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place
- Julie Schneider
- Rush Alzheimer’s Disease Center, Department of Neurological Sciences, Rush University Medical Center
- Mariet Allen
- Mayo Clinic Florida, Department of Neuroscience
- Xue Wang
- Mayo Clinic Florida, Department of Health Sciences Research
- Nilüfer Ertekin-Taner
- Mayo Clinic Florida, Department of Neuroscience
- Nicholas T. Seyfried
- Department of Biochemistry, Emory University School of Medicine
- Allan I. Levey
- Department of Neurology, Emory University School of Medicine
- David A. Bennett
- Rush Alzheimer’s Disease Center, Department of Neurological Sciences, Rush University Medical Center
- Philip L. De Jager
- Center for Translational & Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center
- DOI
- https://doi.org/10.1038/s41467-021-27204-9
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 16
Abstract
Resources reporting RNA editing sites from brain tissue have been published. Here, the authors provide an atlas of RNA editing events found in the aged and Alzheimer’s disease human brain tissue resulting in changes at protein level.
