Long Noncoding RNA PRR34-AS1 Aggravates the Progression of Hepatocellular Carcinoma by Adsorbing microRNA-498 and Thereby Upregulating FOXO3 [Retraction]

Abstract

Liu Z, Li Z, Xu B, Yao H, Qi S, Tai J. Cancer Manag Res. 2020;12:10749–10762. At the authors request, the Editor and Publisher of Cancer Management and Research wish to retract the published article. Following publication of the Expression of Concern for this article the authors contacted the journal and explained they were unable to provide adequate original data for their study. In addition, concerns were also raised regarding the alleged duplication of images in Figure 5E with those from another article. Specifically, Figure 5E, SNU-182, si-PRR34-AS1+miR-498 inhibitor appears to have been duplicated with an image from Figure 4E, H460, agomir-NC from Han et al, 2020 (https://doi.org/10.18632/aging.102628). The authors were unable to provide an explanation for the duplicated images. Our decision-making was informed by our policy on publishing ethics and integrity and the COPE guidelines on retraction. The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as “Retracted”. This retraction relates to this paper

Keywords

• prr34 antisense rna 1
• forkhead box o3
• cerna regulation model
• polymerase chain reaction