Annals of Clinical and Translational Neurology (Aug 2021)

Sarcoidosis and neuromyelitis optica in a patient with optic neuritis – a case report

  • Michael A. Foster,
  • Sara Collorone,
  • Jacqueline Palace,
  • James Acheson,
  • Ahmed T. Toosy

DOI
https://doi.org/10.1002/acn3.51413
Journal volume & issue
Vol. 8, no. 8
pp. 1760 – 1763

Abstract

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Abstract We present a case of atypical recurrent optic neuritis. A man in his 50s presented with right optic neuritis and profound visual loss, associated with elevated inflammatory markers. Lymph‐node biopsy was consistent with sarcoidosis. Aquaporin‐4 antibodies were also present. Three months following corticosteroid treatment, his right optic neuritis relapsed, again with raised inflammatory markers. He was started on azathioprine and prednisolone with good effect. A dual diagnosis of sarcoidosis and neuromyelitis optica with aquaporin‐4 antibodies is very rare. Long‐term immunosuppression is required. The case highlights the importance of identifying the features and cause of atypical optic neuritis.