Molecular Imaging with ¹⁸F-FDG PET/CT and ^99mTc-MIBI SPECT/CT in Osteitis Fibrosa Cystica Generalisata

Abstract

Benign so-called “brown tumors” secondary to hyperparathyroidism are a rare diagnostic pitfall due to their impressively malignant-like character in various imaging modalities. We present the case of a 65-year-old male patient with multiple unclear osteolytic lesions on prior imaging suspicious for metastatic malignant disease. Eventually, findings of 18F-FDG PET/CT staging and 99mTc-MIBI scintigraphy resulted in revision of the initially suspected malignant diagnosis. This case illustrates how molecular imaging findings non-invasively corroborate the correct diagnosis of osteitis fibrosa cystica generalisata with the formation of multiple benign brown tumors.

Keywords

• ¹⁸F-FDG PET/CT
• ^99mTc-MIBI SPECT/CT
• pitfall
• osteitis fibrosa cystica generalisata
• brown tumor
• parathyroid adenoma