Application of Ordered Porous Silica Materials in Drug Delivery: A Review

Wenwen Liu; Junlin Wu; Zehao Jiang; Xinyu Zhang; Zhenxiang Wang; Fanjun Meng; Zidi Liu; Teng Zhang

doi:10.3390/molecules29235713

Molecules (Dec 2024)

Application of Ordered Porous Silica Materials in Drug Delivery: A Review

Wenwen Liu,
Junlin Wu,
Zehao Jiang,
Xinyu Zhang,
Zhenxiang Wang,
Fanjun Meng,
Zidi Liu,
Teng Zhang

Affiliations

Wenwen Liu: Nanjing University of Science and Technology Hospital, Nanjing University of Science and Technology, Nanjing 210094, China
Junlin Wu: School of Chemistry, Chemical Engineering and Materials Science, Shandong Normal University, Jinan 250014, China
Zehao Jiang: School of Chemistry, Chemical Engineering and Materials Science, Shandong Normal University, Jinan 250014, China
Xinyu Zhang: School of Chemistry, Chemical Engineering and Materials Science, Shandong Normal University, Jinan 250014, China
Zhenxiang Wang: School of Chemistry, Chemical Engineering and Materials Science, Shandong Normal University, Jinan 250014, China
Fanjun Meng: School of Chemistry, Chemical Engineering and Materials Science, Shandong Normal University, Jinan 250014, China
Zidi Liu: Big Data and Intelligence Engineering School, Chongqing College of International Business and Economics, Chongqing 401520, China
Teng Zhang: Advanced Technology Research Institute (Jinan), Beijing Institute of Technology, Jinan 250307, China

DOI: https://doi.org/10.3390/molecules29235713
Journal volume & issue: Vol. 29, no. 23
p. 5713

Abstract

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Nanotechnology has significantly advanced various fields, including therapeutic delivery, through the use of nanomaterials as drug carriers. The biocompatibility of ordered porous silica materials makes them promising candidates for drug delivery systems, particularly in the treatment of cancer and other diseases. This review summarizes the use of microporous zeolites and mesoporous silica materials in drug delivery, focusing on their physicochemical properties and applications as drug carriers. Special emphasis is placed on strategies for encapsulation and functionalization, highlighting their role in enhancing drug loading and enabling targeted delivery. In conclusion, while ordered porous silica materials hold great potential for drug delivery systems, certain challenges remain.

Published in Molecules

ISSN: 1420-3049 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Chemistry: Organic chemistry
Website: http://www.mdpi.com/journal/molecules

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