Journal of Clinical and Diagnostic Research (Nov 2013)

Effect of Vitamin E on Uroepithelial Cells and Changes of Urinary Sediments in Oncology Hospital Nursing Personnel

  • Majid Rezaei-Basiri,
  • Hassan Rezazadeh,
  • Iraj Asvadi-Kermani,
  • Mahmud Ghazi-khansari,
  • Mehri Golchin,
  • Mojgan Sarmad

DOI
https://doi.org/10.7860/JCDR/2013/5990.3614
Journal volume & issue
Vol. 7, no. 11
pp. 2570 – 2572

Abstract

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Introduction: Vitamin E is an important natural antioxidant, and its most common and biologically active form is α-tocopherol. The antiproliferative effects of alpha-tocopherol have been previously demonstrated. In this study we investigated the effects of vitamin E on urinary epithelial cells and urinary sediments of nursing from oncology hospital. Material and Methods: Sixty-two female nursing personnel from oncology hospital participated in the study. They received orally 200mg of vitamin E per day for two weeks. Also prior to vitamin E and after vitamin E administration, the uroepithelial cells counts and other components of urinary sediments were carried out. Results: There were significant differences in the epithelial cells count and treatment with vitamin E causing significantly more number of epithelial cells and urinary sediments to be excreted in the urine. Discussion: Vitamin E significantly plays an important role on the excretion of uroepithelial cells and urinary sediments. Conclusion: In conclusion we propose that use of vitamin E at nontoxic levels would significantly enhance its antioxidative properties, especially among individuals subjected to prophylaxis of occupational hazards.

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