Сибирский онкологический журнал (Sep 2017)

POLYSACCHARIDES TUSSILAGOFARFARA L. REDUCE MYELOSUPPRESSION INDUCED BY CISPLATIN AND ETOPOSIDE

  • E. A. Safonova,
  • K. A. Lopatina,
  • T. G. Razina,
  • E. P. Fedorova,
  • E. P. Zueva,
  • A. M. Gurev,
  • M. V. Belousov

DOI
https://doi.org/10.21294/1814-4861-2017-16-4-42-48
Journal volume & issue
Vol. 16, no. 4
pp. 42 – 48

Abstract

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The purpose of the study was to investigate the influence of polysaccharides Tussilagofarfara L. on erythroid sprout hematopoiesis, tumor growth and metastasis in mice with Lung cancer-67 during therapy with cisplatin and etoposide. It was found that the use of polysaccharides reduces myelosuppression induced by cytostatics of erythroidal sprout hematopoiesis and leads to increase anti-tumor and anti-metastatic effect of chemotherapy.

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