Increasing Malaria Parasite Clearance Time after Chloroquine Therapy, South Korea, 2000–2016

Abstract

We reviewed the clinical efficacy of chloroquine for Plasmodium vivax malaria, the changing trend of parasite clearance time, and fever clearance time during 2000–2016 in South Korea. Median parasite clearance time and fever clearance time increased significantly over the study period. Chloroquine was mostly underdosed when used to treat P. vivax malaria.

Keywords

• Chloroquine
• fever clearance time
• hydroxychloroquine
• malaria
• parasite clearance time
• Plasmodium vivax