Recruitment of two Ndc80 complexes via the CENP-T pathway is sufficient for kinetochore functions

Yusuke Takenoshita; Masatoshi Hara; Tatsuo Fukagawa

doi:10.1038/s41467-022-28403-8

Nature Communications (Feb 2022)

Recruitment of two Ndc80 complexes via the CENP-T pathway is sufficient for kinetochore functions

Yusuke Takenoshita,
Masatoshi Hara,
Tatsuo Fukagawa

Affiliations

Yusuke Takenoshita: Graduate School of Frontier Biosciences, Osaka University
Masatoshi Hara: Graduate School of Frontier Biosciences, Osaka University
Tatsuo Fukagawa: Graduate School of Frontier Biosciences, Osaka University

DOI: https://doi.org/10.1038/s41467-022-28403-8
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 19

Abstract

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The kinetochores contain multiple protein interaction networks. Takenoshita et al. analyzed the complicated networks using the genetic method and revealed that two copies of Ndc80 complexes on CENP-T are sufficient for kinetochore functions.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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