The Role of Acyl-CoA β-Oxidation in Brain Metabolism and Neurodegenerative Diseases

Abstract

This review highlights the complex role of fatty acid β-oxidation in brain metabolism. It demonstrates the fundamental importance of fatty acid degradation as a fuel in energy balance and as an essential component in lipid homeostasis, brain aging, and neurodegenerative disorders.

Keywords

• beta-oxidation
• fatty acid metabolism
• brain
• neurodegenerative diseases
• aging