Viscoelastic hemostasis assay guided diagnosis and treatment of trauma-induced coagulopathy

Abstract

The diagnosis and treatment of trauma-induced coagulopathy is an important part of the treatment of severe trauma patients. Trauma-induced coagulopathy has two phenotypes: hypercoagulability and hypocoagulability. The phenotype of coagulopathy in the early stage of trauma patients is variable. Viscoelastic hemostatic assay can reflect the full picture of coagulation in trauma patients. It can guide clinicians to quickly identify different phenotypes of trauma-induced coagulopathy, and fine manage different phenotypes of coagulopathy. This paper introduced the detection methods and principles of common viscoelastic hemostasis assays, and summarized the diagnosis and treatment methods based on viscoelastic hemostasis assay in different phenotypes of trauma-induced coagulopathy from literature, aimed to provide elicitation of diagnosis and treatment for clinicians.

Keywords

• |viscoelastic hemostasis assay|trauma-induced coagulopathy|trauma|thromboelastography|hypercoagulability