Diagnosis and treatment of endocrinological complications of immunotherapy of oncological diseases

Abstract

In this lecture, we discuss in detail the endocrinopathies associated with the use of immune-checkpoint inhibitors in oncology. The cases, terms and features of clinical manifestations of endocrine-related immune reactions are discussed, and practical recommendations for the treatment of patients are proposed.

Keywords

• immune-checkpoint inhibitors
• ipilimumab
• nivolumab
• endocrinopathies
• autoimmune diseases
• adverse effects
• thyroiditis
• pituitary
• adrenal insufficiency
• adrenalitis
• hypothyroidism
• melanoma
• lung cancer
• ctla-4
• pd-1