Effect of Normothermic and Cold Eye Irrigation Solution (BSS) and Viscoelastic Gel on the Consumption of Sedative Drugs in Phacoemulsification Cataract Surgery

Abstract

Abstract Background: This study aimed to compare the effect of cold eye irrigation solution (BSS) and viscoelastic gel with their combination in room temperature on the dosage of sedative drugs which we use in Phacoemulsification cataract surgery. Material and Methods: 190 patients scheduled for cataract surgery under sedation were randomly divided into two equal groups. During surgery, we used cold (4ºc) and warm (room temperature) BSS and viscoelastic gel in the first and second group respectively. For all patients, we started sedation with Midazolam and Fentanyl and in case that we needed additional drug, we used Sodium Thiopental till we reached desired sedation level. Ramsay sedation scores (before, during and after surgery) and total sedative drug consumption were evaluated and compared between two groups and at the end of the surgery, we checked and recorded the satisfaction score of patients and surgeon about the quality of sedation. Results: The average dosage of Midazolam wasn’t significantly different between two groups, while the average dosage of Sodium Thiopental was significantly lower in cold group. Also, the average time on which we reached desired Ramsay sedation score and the level of Ramsay score were significantly different between two groups. Conclusion: Using cold BSS and viscoelastic gel in cataract surgery in comparison of their combination in room temperature will reduce the dosage of sedative drugs which we use during surgery and help us getting a more effective sedation and higher patient and surgeon satisfaction.

Keywords

• Balanced salt solution
• Cataract
• Fentanyl
• Midazolam
• sedation
• Sodium Thiopental
• Viscoelastic gel