Einstein (São Paulo) (Mar 2003)

Influence of female age on blastulation rate of embryo produced by ICSI

  • Jonathas Borges Soares,
  • Sidney Glina,
  • Nelson Antunes Junior,
  • Nadeje Regina Correa,
  • Andrea Giannotti Galuppo,
  • Roberta Wonchockier,
  • Françoise Elia Mizrahi

Journal volume & issue
Vol. 1, no. 1
pp. 15 – 17

Abstract

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OBJECTIVES: There is a tendency to adopt prolonged culture inolder patients; however there are no conclusive results about theinfluence of age on blastulation rate. Therefore, we decided to analyzethe influence of female age on prolonged culture results. METHODS:One hundred and seven ICSI procedures performed in our centerfrom January 1999 to December 2000 were retrospectively analyzed.The blastulation rate was verified and correlated with patient age.RESULTS: In average, 2.8 blastocysts/patient were transferred. Theblastulation rate for each age group was: 180 (32%) in the group 40 years. The statistical analysis demonstrated a significantdifference (p < 0.05). CONCLUSION: The percentage of embryosthat achieved the blastocyst stage was different in each age groupand this percentage dropped as patient age increased. Female agemay influence on blastulation rate of pre-embryos, observing a dropin this rate as patient age increased.

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