Application of the wax moth (Galeria melonella) larvae extract for correction of the immune status of athletes during the recovery period

Abstract

Objective: to study dynamics of parameters of system immunity of athletes during the recovery period against the background of the combined reception of antler bathtubs and extract of larvae of a wax moth. Materials and methods: dynamics of parameters of the immune system of 28 athletes (skiers) had been studied during the recovery period. The main group of athletes (14 people) received antler bathtubs in combination with intake of extract of larvae of a wax moth, and group of comparison - only antler bathtubs. Results: the analysis of the results of the survey showed that the combined reception of the extract of the larvae of the wax moth and antler baths by athletes has a pronounced effect on the dynamics of the studied parameters. The significant augmentation of initially lowered subpopulations of lymphocytes became perceptible (CD3+, CD4+, CD8+). There was an essential depression of concentration of pro-inflammatory cytokines of TNF-a and IL-6 in blood serum and depression of spontaneous production of pro-inflammatory cytokines of TNF-a (p =0,010), IL-6 and IL lß by blood cells. Conclusions: the obtained data confirm the expressed immunomodulatory effect of extract of larvae of a wax moth in athletes during the recovery period.

Keywords

• sports
• immunity
• galleria mellonella
• cytokines
• antlers