Fixed Eruptions: Drug, food, and what more?

Abstract

Fixed drug eruption (FDE) is a common entity encountered in our day-to-day clinical practice. It is a T-cell-dependent pathway with induction of interferon-gamma-producing CD8+ T-cells in the dermis and epidermis. It is not just a drug that causes a fixed eruption but has also been described with food known as fixed food eruption and also with other agents. The article describes the common causes and pathomechanism of FDE.

Keywords

• drug reaction
• fixed drug eruptions
• fixed food eruptions