Foods (Oct 2019)
<i>Berberis</i> Plants—Drifting from Farm to Food Applications, Phytotherapy, and Phytopharmacology
- Bahare Salehi,
- Zeliha Selamoglu,
- Bilge Sener,
- Mehtap Kilic,
- Arun Kumar Jugran,
- Nunziatina de Tommasi,
- Chiara Sinisgalli,
- Luigi Milella,
- Jovana Rajkovic,
- Maria Flaviana B. Morais-Braga,
- Camila F. Bezerra,
- Janaína E. Rocha,
- Henrique D.M. Coutinho,
- Adedayo Oluwaseun Ademiluyi,
- Zabta Khan Shinwari,
- Sohail Ahmad Jan,
- Ebru Erol,
- Zulfiqar Ali,
- Elise Adrian Ostrander,
- Javad Sharifi-Rad,
- María de la Luz Cádiz-Gurrea,
- Yasaman Taheri,
- Miquel Martorell,
- Antonio Segura-Carretero,
- William C. Cho
Affiliations
- Bahare Salehi
- Student Research Committee, School of Medicine, Bam University of Medical Sciences, Bam 44340847, Iran
- Zeliha Selamoglu
- Department of Medical Biology, Faculty of Medicine, Nigde Ömer Halisdemir University, Campus, 51240 Nigde, Turkey
- Bilge Sener
- Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, 06330 Ankara, Turkey
- Mehtap Kilic
- Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, 06330 Ankara, Turkey
- Arun Kumar Jugran
- G.B. Pant National Institute of Himalayan Environment and Sustainable Development, Garhwal Regional Centre, Srinagar 246174, Uttarakhand, India
- Nunziatina de Tommasi
- Department of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, 84084 Fisciano, Italy
- Chiara Sinisgalli
- Department of Science, University of Basilicata, Viale dell’Ateneo Lucano 10, 85100 Potenza, Italy
- Luigi Milella
- Department of Science, University of Basilicata, Viale dell’Ateneo Lucano 10, 85100 Potenza, Italy
- Jovana Rajkovic
- Institute of Pharmacology, Clinical Pharmacology and Toxicology, Medical Faculty, University of Belgrade, 11129 Belgrade, Serbia
- Maria Flaviana B. Morais-Braga
- Laboratory of Applied Micology of Cariri—LMAC, Regional University of Cariri—URCA, Crato 63105-000, CE, Brazil
- Camila F. Bezerra
- Laboratory of Applied Micology of Cariri—LMAC, Regional University of Cariri—URCA, Crato 63105-000, CE, Brazil
- Janaína E. Rocha
- Laboratory of Microbiology and Molecular Biology—LMBM, Regional University of Cariri—URCA, Crato 63105-000, CE, Brazil
- Henrique D.M. Coutinho
- Laboratory of Microbiology and Molecular Biology—LMBM, Regional University of Cariri—URCA, Crato 63105-000, CE, Brazil
- Adedayo Oluwaseun Ademiluyi
- Functional Foods, Nutraceuticals and Phytomedicine Unit, Department of Biochemistry, Federal University of Technology, Akure 340252, Nigeria
- Zabta Khan Shinwari
- Department of Biotechnology, Quaid-i-Azam University, Islamabad 45320, Pakistan
- Sohail Ahmad Jan
- Department of Biotechnology, Hazara University Mansehra, Khyber Pakhtunkhwa 21120, Pakistan
- Ebru Erol
- Department of Chemistry, Faculty of Science, Mugla Sitki Kocman University, Mugla 48121, Turkey
- Zulfiqar Ali
- National Center for Natural Products Research, School of Pharmacy, University of Mississippi, Oxford, MS 38677, USA
- Elise Adrian Ostrander
- Medical Illustration, Kendall College of Art and Design, Ferris State University, Grand Rapids, MI 49501, USA
- Javad Sharifi-Rad
- Department of Pharmacology, Faculty of Medicine, Jiroft University of Medical Sciences, Jiroft 7861756447, Iran
- María de la Luz Cádiz-Gurrea
- Department of Analytical Chemistry, Faculty of Sciences, University of Granada, Avda. Fuentenueva s/n, 18071 Granada, Spain
- Yasaman Taheri
- Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran 1991953381, Iran
- Miquel Martorell
- Department of Nutrition and Dietetics, Faculty of Pharmacy, University of Concepcion, Concepcion 4070386, Chile
- Antonio Segura-Carretero
- Department of Analytical Chemistry, Faculty of Sciences, University of Granada, Avda. Fuentenueva s/n, 18071 Granada, Spain
- William C. Cho
- Department of Clinical Oncology, Queen Elizabeth Hospital, 30 Gascoigne Road, Hong Kong, China
- DOI
- https://doi.org/10.3390/foods8100522
- Journal volume & issue
-
Vol. 8,
no. 10
p. 522
Abstract
The genus Berberis includes about 500 different species and commonly grown in Europe, the United States, South Asia, and some northern areas of Iran and Pakistan. Leaves and fruits can be prepared as food flavorings, juices, and teas. Phytochemical analysis of these species has reported alkaloids, tannins, phenolic compounds and oleanolic acid, among others. Moreover, p-cymene, limonene and ocimene as major compounds in essential oils were found by gas chromatography. Berberis is an important group of the plants having enormous potential in the food and pharmaceutical industry, since they possess several properties, including antioxidant, antimicrobial, anticancer activities. Here we would like to review the biological properties of the phytoconstituents of this genus. We emphasize the cultivation control in order to obtain the main bioactive compounds, the antioxidant and antimicrobial properties in order to apply them for food preservation and for treating several diseases, such as cancer, diabetes or Alzheimer. However, further study is needed to confirm the biological efficacy as well as, the toxicity.
Keywords
