Histological, Immunohistological, and Clinical Features of  Merkel Cell Carcinoma in Correlation to Merkel Cell Polyomavirus Status

T. Jaeger; J. Ring; C. Andres

doi:10.1155/2012/983421

Journal of Skin Cancer (Jan 2012)

Histological, Immunohistological, and Clinical Features of Merkel Cell Carcinoma in Correlation to Merkel Cell Polyomavirus Status

T. Jaeger,
J. Ring,
C. Andres

Affiliations

T. Jaeger: Department of Dermatology and Allergy Biederstein, Technische Universität München, 80802 Munich, Germany
J. Ring: Department of Dermatology and Allergy Biederstein, Technische Universität München, 80802 Munich, Germany
C. Andres: Department of Dermatology and Allergy Biederstein, Technische Universität München, 80802 Munich, Germany

DOI: https://doi.org/10.1155/2012/983421
Journal volume & issue: Vol. 2012

Abstract

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Merkel cell carcinoma is a rare, but highly malignant tumor of the skin with high rates of metastasis and poor survival. Its incidence rate rises and is currently about 0.6/100000/year. Clinical differential diagnoses include basal cell carcinoma, cyst, amelanotic melanoma, lymphoma and atypical fibroxanthoma. In this review article clinical, histopathological and immunhistochemical features of Merkel cell carcinoma are reported. In addition, the role of Merkel cell polyomavirus is discussed.

Published in Journal of Skin Cancer

ISSN: 2090-2905 (Print); 2090-2913 (Online)
Publisher: Hindawi Limited
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: https://onlinelibrary.wiley.com/journal/9158

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