Nature Communications (Jun 2019)

DNA double-strand breaks in telophase lead to coalescence between segregated sister chromatid loci

  • Jessel Ayra-Plasencia,
  • Félix Machín

DOI
https://doi.org/10.1038/s41467-019-10742-8
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 14

Abstract

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The mechanism regulating DNA repair in late anaphase or telophase is not yet clear. Here authors reveal that DNA double strand breaks in telophase causes a partial reversal of sister chromosome segregation which could create an opportunity of using the sister for repair in telophase.