Clinical case of giant desmoid abdominal fibroma

Abstract

Background. Desmoid fibroma is a fibroblastic neoplasm of intermediate biological significance without metastatic potential, but with a tendency to local recurrence and infiltration of surrounding tissues. These tumors are extremely rare (2-4 cases per 1 million people). Information about desmoid fibromatosis is presented in isolated publications. The purpose of the study: to describe a clinical case of desmoid abdominal fibroma in a man of working age, including: identification of the features of the histological picture of the tumor, interpretation of the results of immunohistochemical examination, differential diagnosis with other diseases. Materials and methods. The data of the results of multispiral computed tomography (MSCT) of abdominal organs, macroscopic and microscopic examination of surgical material in the form of tumors, fragments of the abdominal cavity, omentum and aponeurosis, immunohistochemical examination with the following markers: CD34, CD31, LMO2, Podoplanin, CD68, anti-S100, HMB45, B-Catenin, SMA, Desmin. Results and conclusions. In this study, an analysis of a clinical case of rare abdominal fibroma was presented, and important points for differential diagnosis with other soft tissue neoplasms were identified. Raising awareness on this topic increases the likelihood of timely detection and verification of desmoid fibroma.

Keywords

• desmoid fibroma
• abdominal desmoid
• abdominal desmoid fibroma