Data of methylome and transcriptome derived from human dilated cardiomyopathy

Bong-Seok Jo; In-Uk Koh; Jae-Bum Bae; Ho-Yeong Yu; Eun-Seok Jeon; Hae-Young Lee; Jae-Joong Kim; Murim Choi; Sun Shim Choi

doi:10.1016/j.dib.2016.09.006

Data in Brief (Dec 2016)

Data of methylome and transcriptome derived from human dilated cardiomyopathy

Bong-Seok Jo,
In-Uk Koh,
Jae-Bum Bae,
Ho-Yeong Yu,
Eun-Seok Jeon,
Hae-Young Lee,
Jae-Joong Kim,
Murim Choi,
Sun Shim Choi

Affiliations

Bong-Seok Jo: Division of Biomedical Convergence, College of Biomedical Science, and Institute of Bioscience & Biotechnology, Kangwon National University, Chuncheon 24341, South Korea
In-Uk Koh: Division of Structural and Functional Genomics, Center of Genome Science, National Research Institute of Health, Chuncheongbuk-do 28159, South Korea
Jae-Bum Bae: Division of Structural and Functional Genomics, Center of Genome Science, National Research Institute of Health, Chuncheongbuk-do 28159, South Korea
Ho-Yeong Yu: Division of Structural and Functional Genomics, Center of Genome Science, National Research Institute of Health, Chuncheongbuk-do 28159, South Korea
Eun-Seok Jeon: Division of Cardiology, Cardiac and Vascular Center, Department of Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon 51353, South Korea
Hae-Young Lee: Division of Cardiology, Seoul National University College of Medicine, Seoul 03080, South Korea
Jae-Joong Kim: Division of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 44033, South Korea
Murim Choi: Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, South Korea
Sun Shim Choi: Division of Biomedical Convergence, College of Biomedical Science, and Institute of Bioscience & Biotechnology, Kangwon National University, Chuncheon 24341, South Korea

DOI: https://doi.org/10.1016/j.dib.2016.09.006
Journal volume & issue: Vol. 9, no. C
pp. 382 – 387

Abstract

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Alterations in DNA methylation and gene expression have been implicated in the development of human dilated cardiomyopathy (DCM). Differentially methylated probes (DMPs) and differentially expressed genes (DEGs) were identified between the left ventricle (LV, a pathological locus for DCM) and the right ventricle (RV, a proxy for normal hearts). The data in this DiB are for supporting our report entitled “Methylome analysis reveals alterations in DNA methylation in the regulatory regions of left ventricle development genes in human dilated cardiomyopathy” (Bong-Seok Jo, In-Uk Koh, Jae-Bum Bae, Ho-Yeong Yu, Eun-Seok Jeon, Hae-Young Lee, Jae-Joong Kim, Murim Choi, Sun Shim Choi, 2016) [1].

Published in Data in Brief

ISSN: 2352-3409 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Computer applications to medicine. Medical informatics; Science: Science (General)
Website: http://www.journals.elsevier.com/data-in-brief/

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