S135: CRISPR/CAS9 EDITING REVEALS DEPENDENCE OF HUMAN RICHTER SYNDROME AND MURINE CLL CELLS ON SIGNALS FROM B CELL RECEPTOR, CXCR4 RECEPTOR AND MACROPHAGES BUT NOT FROM TOLL-LIKE RECEPTORS IN VIVO

• C. Martines,
• S. Chakraborty,
• V. Guastafierro,
• M. Vujovikj,
• T. Vaisitti,
• S. Deaglio,
• L. Laurenti,
• A. Dimovski,
• D. Efremov

Affiliations

C. Martines

1 Molecular Hematology, International Centre for Genetic Engineering and Biotechnology, Trieste, Italy

S. Chakraborty

1 Molecular Hematology, International Centre for Genetic Engineering and Biotechnology, Trieste, Italy

V. Guastafierro

1 Molecular Hematology, International Centre for Genetic Engineering and Biotechnology, Trieste, Italy

M. Vujovikj

2 Research Center for Genetic Engineering and Biotechnology, Macedonian Academy of Sciences and Arts, Skopje, North Macedonia, Republic of

T. Vaisitti

3 Functional Genomics Unit, Department of Medical Sciences, University of Turin, Torino

S. Deaglio

3 Functional Genomics Unit, Department of Medical Sciences, University of Turin, Torino

L. Laurenti

4 Department of Hematology, Catholic University Hospital “A. Gemelli”, Rome, Italy

A. Dimovski

2 Research Center for Genetic Engineering and Biotechnology, Macedonian Academy of Sciences and Arts, Skopje, North Macedonia, Republic of

D. Efremov

1 Molecular Hematology, International Centre for Genetic Engineering and Biotechnology, Trieste, Italy