Myosin light-chain phosphatase regulates basal actomyosin oscillations during morphogenesis

Abstract

Actomyosin contractility is regulated by phosphorylation of myosin regulatory light chain; much of the work in this area has focused on the kinase. Here the authors use Drosophilafollicle cells and modelling to show that the phosphatase subunit Flapwing controls the initiation and dynamics of actomyosin oscillations.