Admission plasma glucose and maternal prognostic factors in preeclampsia

Abstract

Aims: We aimed to investigate if admission plasma glucose (PG) level was a significant and independent risk factor for the patients' length of stay at the intensive care unit (ICU), as the primary outcome parameter, and also for the maternal and fetal complications, as the secondary outcome parameters, among a group of nondiabetic pregnant women with severe preeclampsia. Materials and Methods: In this prospective case–control study including 63 pregnant women, admission PG, glycosylated hemoglobin, neutrophil–lymphocyte ratio, platelet count, liver enzymes, and other laboratory parameters and clinical characteristics including length of stay at the hospital, maternal, and fetal complications were investigated. Results: Admission PG levels were found to be significantly elevated in preeclamptic women with poor outcome. Furthermore, platelet count, fibrinogen, alanine aminotransferase, and aspartate aminotransferase values were significantly associated with the length of stay at ICU. Conclusion: We claimed that hyperglycemia was an acute reaction, reflecting the severity of preeclampsia and PG levels to be added to the routine high-risk pregnancy panel on initial presentation to the hospital.

Keywords

• eclampsia
• fibrinogen
• glycosylated hemoglobin
• hellp syndrome
• intensive care unit
• neutrophil
• platelet