South African Journal of Radiology (Aug 2000)
A trio of multiple Wilms' tumours
Abstract
Wilms' tumour is the commonest malignant abdominal tumour in children. Unilateral multicentric, and bilateral Wilms' tumours are, however, less common, occurring in 7% and 5% of cases respectively. These are often associated with sporadic aniridia, genitourinary anomalies, hemihypertrophy and nephroblastomatosis. Nephroblastomatosis is a separate entity that may act as a precursor of Wilms' tumours. We present three cases of multiple Wilms' tumours. Two cases also had nephroblastomatosis which was not seen on pre-operative CT imaging but was identified in one case at MRI. In cases of multiple Wilms' tumours, MRI provides better delineation of the tumours and may, therefore, affect management.
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