Cardiac adipose tissue volume assessed by computed tomography is a specific and independent predictor of early mortality and critical illness in COVID-19 in type 2-diabetic patients

Abstract

Keypoints Prognostic value of pericardiac fat tissue assessed using CT to predict adverse outcomes for T2D patients admitted for COVID-19 infection A disctinct phenotypic pattern was found between diabetic patients and controls with respect to adverse outcom:. classicl risk factors such as age or sex adetermine the prognosis in controls whereas the metabolic and inflammatory profile determine outcome in diabetics. Fast and reliable measurement of cardiac adipose tissue using CT. The assessment of this parameter could be useful to better stratify individual risk in diabetic patients with COVID-19 and adapt patient management of patients in routine practice.

Keywords

• Type 2 diabetes (T2D)
• Cardiac adipose tissue
• Computed tomography
• COVID-19
• Mortality
• Intensive care