Enterovirus D68–Associated Acute Flaccid Myelitis in Immunocompromised Woman, Italy

Abstract

In Italy in 2016, acute flaccid myelitis developed in a woman who had received a hematopoietic stem cell transplant. Enterovirus D68 viral genome was detected in respiratory and cerebrospinal fluid samples, and the viral protein 1 sequence clustered with lineage B3. Immunocompromised adults may be at risk for enterovirus D68–associated neurologic complications.

Keywords

• Enterovirus-D68
• human
• CNS infection
• VP1 sequencing
• molecular epidemiology
• immunocompromised patient