Antioxidant-rich peridialytic granola bar for hemodialytic subjects

Abstract

Background: Chronic kidney disease is an emerging major noncommunicable health problem globally. The hemodialysis procedure results with increase in lipid peroxidation and decrease in antioxidant enzymes such as superoxide dismutase with change in serum antioxidant activity. The aim of the study is to formulate an antioxidant-rich peridialytic granola bar to supplement hemodialysis patients. Methods: The recipe was formulated using oats, ground nuts, dehydrated papaya, flax seeds, almonds, honey, and vegetable oil. To make the supplement antioxidant-rich, dehydrated papaya, honey, and vegetable oil have been selected. Results: The amount of antioxidant in the analyzed peridialytic granola bar has been compared with the recommended dietary allowance (RDA) for the hemodialysis patients and the quantity for supplementation has been finalized. The 80 g of peridialytic granola bar provides around 3369.6 μg of antioxidant, 15 g of protein, and 346.4 kcal of energy to meet the two-third of the recommended antioxidants and one-fourth of the protein and energy. Conclusion: The composition of the developed bar was standardized through organoleptic evaluation. The antioxidant content of the developed product was analyzed and compared with RDA. Eighty grams, i.e., 2 numbers of peridialytic granola bar, will provide roughly around 3369.6 μg of antioxidant, 15 g of protein, and 346.4 kcal of energy. This nutritional value is equivalent to approximately 1 serving of standard commercial formulas of 50 g. The formulated antioxidant-rich peridialytic granola bar can be considered for supplementation for 4 weeks to the subjects undergoing hemodialysis to reduce their oxidative stress.

Keywords

• antioxidant
• oxidative stress
• peridialytic
• peridialytic granola bar