Single-particle imaging of stress-promoters induction reveals the interplay between MAPK signaling, chromatin and transcription factors

Victoria Wosika; Serge Pelet

doi:10.1038/s41467-020-16943-w

Nature Communications (Jun 2020)

Single-particle imaging of stress-promoters induction reveals the interplay between MAPK signaling, chromatin and transcription factors

Victoria Wosika,
Serge Pelet

Affiliations

Victoria Wosika: Department of Fundamental Microbiology, University of Lausanne
Serge Pelet: Department of Fundamental Microbiology, University of Lausanne

DOI: https://doi.org/10.1038/s41467-020-16943-w
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 13

Abstract

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Mitogen-Activated Protein Kinases integrate extracellular information in all eukaryotic cells. Using a live mRNA reporter, here the authors monitor transcriptional bursting in Saccharomyces cerevisiae upon hyper-osmotic shock and characterize the influence of MAPK signalling, chromatin and transcription factors on the dynamics of transcription.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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