Catalytically inactive Gla-domainless factor Xa binds to TFPI and restores ex vivo coagulation in hemophilia plasma

• Atanur Ersayin,
• Aline Thomas,
• Landry Seyve,
• Nicole Thielens,
• Mathieu Castellan,
• Raphaël Marlu,
• Benoît Polack,
• Marie-Claire Dagher

Affiliations

Atanur Ersayin

University of Grenoble Alpes, CNRS, CHU Grenoble Alpes, Grenoble INP, TIMC-IMAG, Institute of Engineering, University Grenoble Alpes, Grenoble, France

Aline Thomas

University of Grenoble Alpes, CNRS, DPM, Grenoble, France

Landry Seyve

University of Grenoble Alpes, CNRS, CHU Grenoble Alpes, Grenoble INP, TIMC-IMAG, Institute of Engineering, University Grenoble Alpes, Grenoble, France

Nicole Thielens

University of Grenoble Alpes, CEA, CNRS, IBS, Grenoble, France

Mathieu Castellan

University of Grenoble Alpes, CNRS, CHU Grenoble Alpes, Grenoble INP, TIMC-IMAG, Institute of Engineering, University Grenoble Alpes, Grenoble, France

Raphaël Marlu

University of Grenoble Alpes, CNRS, CHU Grenoble Alpes, Grenoble INP, TIMC-IMAG, Institute of Engineering, University Grenoble Alpes, Grenoble, France

Benoît Polack

University of Grenoble Alpes, CNRS, CHU Grenoble Alpes, Grenoble INP, TIMC-IMAG, Institute of Engineering, University Grenoble Alpes, Grenoble, France

Marie-Claire Dagher

University of Grenoble Alpes, CNRS, CHU Grenoble Alpes, Grenoble INP, TIMC-IMAG, Institute of Engineering, University Grenoble Alpes, Grenoble, France