Проблемы особо опасных инфекций (Dec 2014)

Toxicity of Various Forms of <I>Yersinia pestis</I> Lipopolysaccharides to D-Galactosamine Sensitized White Mice

  • G. V. Demidova,
  • V. P. Zyuzina,
  • E. P. Sokolova,
  • N. I. Pasyukova,
  • I. A. Bespalova,
  • T. N. Borodina,
  • V. I. Tynyanova

DOI
https://doi.org/10.21055/0370-1069-2014-4-75-77
Journal volume & issue
Vol. 0, no. 4
pp. 75 – 77

Abstract

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equals 520÷610 mcg/mouse. Sensitivity of the animals to the stated above LPS forms’ effect when affected by D-GalN is by two orders greater, and as for LPS of the virulent strain is by three orders. Concurrently, differences in toxicity properties in the original (LPS37) and conformationally altered (LPS37-MT) LPS-forms in both of the tested Y. pestis strains drop out of the equation completely.

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