An educational intervention on attitudes in pharmacovigilance and adverse drug reactions reports among health-care professionals in a public hospital in the State of Mexico: An interventional and prospective assessment

Abstract

There are few studies on pharmacovigilance (pv) and adverse drug reactions (adr) in Mexico. The aim was to assess the effect of a pharmacovigilance training program on attitudes among healthcare professionals in a public hospital in Mexico State. This study was conducted in 100 physicians and nurses. A questionnaire was designed to assess attitudes in pv; its reliability was determined with Cronbach’s alpha coefficient and criterion validity with Delphi method and applied it. Based on the needs detected, a training program was designed, applied to healthcare professionals and yet again the questionnaire was applied. In addition, adverse drug reaction reports were reviewed and compared using Wilcoxon signed-rank test. A factor analysis was performed to identify the questionnaire’ main components. After the intervention, there were statistically significant differences; the number of monthly reports of suspected adr significantly aroused, also improving the quality of the information collected. This study showed how an educational intervention helps increase positive abilities and attitudes about pv and adr reports among healthcare professionals.

Keywords

• attitudes in pharmacovigilance
• educational intervention
• adverse drug reactions