Nature Communications (Jan 2018)
Maturation of the gut microbiome and risk of asthma in childhood
- Jakob Stokholm,
- Martin J. Blaser,
- Jonathan Thorsen,
- Morten A. Rasmussen,
- Johannes Waage,
- Rebecca K. Vinding,
- Ann-Marie M. Schoos,
- Asja Kunøe,
- Nadia R. Fink,
- Bo L. Chawes,
- Klaus Bønnelykke,
- Asker D. Brejnrod,
- Martin S. Mortensen,
- Waleed Abu Al-Soud,
- Søren J. Sørensen,
- Hans Bisgaard
Affiliations
- Jakob Stokholm
- COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen
- Martin J. Blaser
- Departments of Medicine and Microbiology, and the Human Microbiome Program, New York University Langone Medical Center
- Jonathan Thorsen
- COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen
- Morten A. Rasmussen
- COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen
- Johannes Waage
- COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen
- Rebecca K. Vinding
- COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen
- Ann-Marie M. Schoos
- COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen
- Asja Kunøe
- COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen
- Nadia R. Fink
- COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen
- Bo L. Chawes
- COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen
- Klaus Bønnelykke
- COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen
- Asker D. Brejnrod
- Section of Microbiology, Department of Biology, University of Copenhagen
- Martin S. Mortensen
- Section of Microbiology, Department of Biology, University of Copenhagen
- Waleed Abu Al-Soud
- Section of Microbiology, Department of Biology, University of Copenhagen
- Søren J. Sørensen
- Section of Microbiology, Department of Biology, University of Copenhagen
- Hans Bisgaard
- COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen
- DOI
- https://doi.org/10.1038/s41467-017-02573-2
- Journal volume & issue
-
Vol. 9,
no. 1
pp. 1 – 10
Abstract
Colonization of commensal bacteria is thought to impact immune development, especially in the earliest years of life. Here, the authors show, by analyzing the development of the gut microbiome of 690 children, that microbial composition at the age of 1 year is associated with asthma diagnosed in the first 5 years of life.
