Microbiological features of bronchial asthma and chronic obstructive pulmonary disease during remission

Abstract

Background: Bronchial asthma and chronic obstructive pulmonary disease are currently the fifth leading cause of death in the world. The combination of bronchial asthma and chronic obstructive pulmonary disease seems to be a unique disease resulting from the interaction of genetic, pathological and functional factors. Aim: Study of clinical and functional parameters, bacterial spectrum in patients with combination of asthma and chronic obstructive pulmonary diseases bronchitis and non-bronchitis types. Methods: Clinical and functional examination of 69 patients with obstructive respiratory diseases, of which 49 patients with asthma combined with chronic obstructive pulmonary disease of bronchitis and non-bronchitis types. The microbiological spectrum of nasal pharynx induced by sputum was studied. Results: The following microorganisms were isolated: Staphylococcus (S. aureus, S. epidermidis), Neisseria subflava, Streptococcus (-haemolyticus, -haemolyticus), Streptococcus pneumoniae, Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Branhamella catarrhalis, Enterococcus, Haemophilus influenzae, Candida albicans, Aspergillus spp., Actinomyces spp., Cladosporium, Penicillium, and others. Conclusion: A more pronounced quantitative content and a more diverse microbial landscape leads to a more severe course of the disease asthma combined withchronic obstructive pulmonary disease especially of the bronchitis type.

Keywords

• microbiological spectrum
• bronchial asthma
• chronic obstructive pulmonary diseases