Indian Journal of Urology (Jan 2001)
Management of idiopathic oligoasthenospermia with lycopene
Abstract
Idiopathic oligoasthenosperinia accounts. for almost 24% of all male infertility. The role of free radicals as a cause of such male infertility has been established recently. We undertook a study to establish the role of Lycopene (antioxidant) in management of such infertile males due to free radicals. A total number of 50 patients having no obvious cause for their infertility with normal hormone profile and antisperin antibody titre but showing oligoasthenospermia were given Lycopene (Lycored) 8 mg daily till their sperm analysis improved to optimal level or pregnancy was achieved. Regular, follow-up for one year with sperm analysis was done. Result showed a 36% pregnancy rate with improvement of sperm count and functional sperm concentration in 70% and 60% respectively, sperm motility and sperm motility index improved in 54% and 46% while 38% showed improvement in sperm morphology. There were no side effects with good patient compliance. Conclusion: Lycopene supplementation has a definite role in management of idiopathic oligoasthenospermia.
