Giant orbital schwannoma with cystic degeneration in a young female managed with extended enucleation

Abstract

Schwannomas are benign, slow-growing, and noninvasive tumors. They account for 1% of all orbital tumors. A 32-year-old female patient presented with a large mass and proptosis of the right eye for 4 years. On imaging, a large well-defined mass, heterogeneous mass of the right orbit with the evidence of cystic degeneration, was present. On incisional biopsy, fusiform cells arranged in intertwine bundles with characteristic Verocay bodies (Antoni A) and multiple cystic regions (Antoni B patterns) were found. S-100 was found positive on IHC, and a diagnosis of schwannoma was made. Cystic degeneration in orbital schwannoma has also been reported but very rarely.

Keywords

• cystic degeneration
• extended enucleation
• orbital schwannoma
• schwannoma