Scientific Reports (Jul 2023)

Enhancement of solute diffusion in microdroplets using microrotors under rotational magnetic field

  • Shinji Bono,
  • Kota Sakai,
  • Satoshi Konishi

DOI
https://doi.org/10.1038/s41598-023-38299-z
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 8

Abstract

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Abstract In vertical contact control (VCC), a microdroplet array selectively contacts with an opposite microdroplet array. Generally, VCC is useful for the dispenser mechanism based on solute diffusion between microdroplet pairs. However, sedimentation due to gravity can cause an inhomogeneous distribution of solutes in microdroplets. Therefore, it is necessary to enhance solute diffusion to achieve the accurate dispensing of a large quantity of solute in the direction opposite to that of gravity. Herein, we applied a rotational magnetic field to the microrotors in microdroplets to enhance the solute diffusion in microdroplets. Driven by microrotors, the rotational flow can generate a homogeneous distribution of solutes in microdroplets. We analyzed the diffusion dynamics of solutes using a phenomenological model, and the results showed that the rotation of microrotors can increase the diffusion constant of solutes.