Nature Communications (Jun 2021)

R2DT is a framework for predicting and visualising RNA secondary structure using templates

  • Blake A. Sweeney,
  • David Hoksza,
  • Eric P. Nawrocki,
  • Carlos Eduardo Ribas,
  • Fábio Madeira,
  • Jamie J. Cannone,
  • Robin Gutell,
  • Aparna Maddala,
  • Caeden D. Meade,
  • Loren Dean Williams,
  • Anton S. Petrov,
  • Patricia P. Chan,
  • Todd M. Lowe,
  • Robert D. Finn,
  • Anton I. Petrov

DOI
https://doi.org/10.1038/s41467-021-23555-5
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 12

Abstract

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Non-coding RNA function is poorly understood, partly due to the challenge of determining RNA secondary (2D) structure. Here, the authors present a framework for the reproducible prediction and visualization of the 2D structure of a wide array of RNAs, which enables linking RNA sequence to function.