The Effect of Diabetes and Hyperglycemia on Horizontal Guided Bone Regeneration: A Clinical Prospective Analysis

Paolo De Angelis; Edoardo Rella; Paolo Francesco Manicone; Giuseppe De Rosa; Sofia Gallottini; Margherita Giorgia Liguori; Piero Papi; Viviana Desantis; Pier Carmine Passarelli; Antonio D’Addona

doi:10.3390/healthcare11121801

Healthcare (Jun 2023)

The Effect of Diabetes and Hyperglycemia on Horizontal Guided Bone Regeneration: A Clinical Prospective Analysis

Paolo De Angelis,
Edoardo Rella,
Paolo Francesco Manicone,
Giuseppe De Rosa,
Sofia Gallottini,
Margherita Giorgia Liguori,
Piero Papi,
Viviana Desantis,
Pier Carmine Passarelli,
Antonio D’Addona

Affiliations

Paolo De Angelis: Department of Head and Neck and Sensory Organs, Division of Oral Surgery and Implantology, Fondazione Policlinico Universitario A. Gemelli IRCCS—Università Cattolica del Sacro Cuore, 00168 Rome, Italy
Edoardo Rella: Department of Head and Neck and Sensory Organs, Division of Oral Surgery and Implantology, Fondazione Policlinico Universitario A. Gemelli IRCCS—Università Cattolica del Sacro Cuore, 00168 Rome, Italy
Paolo Francesco Manicone: Department of Head and Neck and Sensory Organs, Division of Oral Surgery and Implantology, Fondazione Policlinico Universitario A. Gemelli IRCCS—Università Cattolica del Sacro Cuore, 00168 Rome, Italy
Giuseppe De Rosa: Department of Head and Neck and Sensory Organs, Division of Oral Surgery and Implantology, Fondazione Policlinico Universitario A. Gemelli IRCCS—Università Cattolica del Sacro Cuore, 00168 Rome, Italy
Sofia Gallottini: Department of Head and Neck and Sensory Organs, Division of Oral Surgery and Implantology, Fondazione Policlinico Universitario A. Gemelli IRCCS—Università Cattolica del Sacro Cuore, 00168 Rome, Italy
Margherita Giorgia Liguori: Department of Life, Health and Environmental Sciences, Università degli Studi dell’Aquila, 67100 L’Aquila, Italy
Piero Papi: Department of Oral and Maxillo-Facial Sciences, Sapienza University of Rome, 00168 Rome, Italy
Viviana Desantis: Department of Oral Surgery, University of Milan, 20122 Milan, Italy
Pier Carmine Passarelli: Department of Head and Neck and Sensory Organs, Division of Oral Surgery and Implantology, Fondazione Policlinico Universitario A. Gemelli IRCCS—Università Cattolica del Sacro Cuore, 00168 Rome, Italy
Antonio D’Addona: Department of Head and Neck and Sensory Organs, Division of Oral Surgery and Implantology, Fondazione Policlinico Universitario A. Gemelli IRCCS—Università Cattolica del Sacro Cuore, 00168 Rome, Italy

DOI: https://doi.org/10.3390/healthcare11121801
Journal volume & issue: Vol. 11, no. 12
p. 1801

Abstract

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Guided bone regeneration (GBR) is a reconstructive procedure for treating atrophic alveolar ridges. This study aims to assess the correlation between different glycemic control levels and clinical findings in patients undergoing horizontal GBR before implant placement. The study population consisted of all patients requiring horizontal GBR. Patients were divided into three groups based on HbA1c levels: non-diabetic normoglycemic patients (HbA1c p = 0.026) and between group 1 and group 3 (p = 0.030). The present investigation showed that patients with HbA1c levels below 7% could undergo GBR and obtain a statistically significant horizontal bone gain.

Published in Healthcare

ISSN: 2227-9032 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Medicine
Website: http://www.mdpi.com/journal/healthcare

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