Nature Communications (Aug 2022)
Connecting omics signatures and revealing biological mechanisms with iLINCS
- Marcin Pilarczyk,
- Mehdi Fazel-Najafabadi,
- Michal Kouril,
- Behrouz Shamsaei,
- Juozas Vasiliauskas,
- Wen Niu,
- Naim Mahi,
- Lixia Zhang,
- Nicholas A. Clark,
- Yan Ren,
- Shana White,
- Rashid Karim,
- Huan Xu,
- Jacek Biesiada,
- Mark F. Bennett,
- Sarah E. Davidson,
- John F. Reichard,
- Kurt Roberts,
- Vasileios Stathias,
- Amar Koleti,
- Dusica Vidovic,
- Daniel J. B. Clarke,
- Stephan C. Schürer,
- Avi Ma’ayan,
- Jarek Meller,
- Mario Medvedovic
Affiliations
- Marcin Pilarczyk
- Department of Environmental and Public Health Sciences, University of Cincinnati
- Mehdi Fazel-Najafabadi
- Department of Environmental and Public Health Sciences, University of Cincinnati
- Michal Kouril
- LINCS Data Coordination and Integration Center (DCIC)
- Behrouz Shamsaei
- Department of Environmental and Public Health Sciences, University of Cincinnati
- Juozas Vasiliauskas
- Department of Environmental and Public Health Sciences, University of Cincinnati
- Wen Niu
- Department of Environmental and Public Health Sciences, University of Cincinnati
- Naim Mahi
- Department of Environmental and Public Health Sciences, University of Cincinnati
- Lixia Zhang
- Department of Environmental and Public Health Sciences, University of Cincinnati
- Nicholas A. Clark
- Department of Environmental and Public Health Sciences, University of Cincinnati
- Yan Ren
- Department of Environmental and Public Health Sciences, University of Cincinnati
- Shana White
- Department of Environmental and Public Health Sciences, University of Cincinnati
- Rashid Karim
- Department of Environmental and Public Health Sciences, University of Cincinnati
- Huan Xu
- Department of Environmental and Public Health Sciences, University of Cincinnati
- Jacek Biesiada
- Department of Environmental and Public Health Sciences, University of Cincinnati
- Mark F. Bennett
- Department of Environmental and Public Health Sciences, University of Cincinnati
- Sarah E. Davidson
- Department of Environmental and Public Health Sciences, University of Cincinnati
- John F. Reichard
- Department of Environmental and Public Health Sciences, University of Cincinnati
- Kurt Roberts
- Department of Environmental and Public Health Sciences, University of Cincinnati
- Vasileios Stathias
- LINCS Data Coordination and Integration Center (DCIC)
- Amar Koleti
- LINCS Data Coordination and Integration Center (DCIC)
- Dusica Vidovic
- LINCS Data Coordination and Integration Center (DCIC)
- Daniel J. B. Clarke
- LINCS Data Coordination and Integration Center (DCIC)
- Stephan C. Schürer
- LINCS Data Coordination and Integration Center (DCIC)
- Avi Ma’ayan
- LINCS Data Coordination and Integration Center (DCIC)
- Jarek Meller
- Department of Environmental and Public Health Sciences, University of Cincinnati
- Mario Medvedovic
- Department of Environmental and Public Health Sciences, University of Cincinnati
- DOI
- https://doi.org/10.1038/s41467-022-32205-3
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 13
Abstract
There are only a few platforms that integrate multiple omics data types, bioinformatics tools, and interfaces for integrative analyses and visualization that do not require programming skills. Here the authors present an integrative web-based platform for analysis of omics data and signatures of cellular perturbations.