Psychopharmacogenetic approach in therapy of affective disorders depressive spectrum

Abstract

This article is dedicated to rationale of pharmacotherap y in the treatment of depressive disorders. Differentiation of allele gene variances, linked to metabolism of antidepressants, was conducted. Genetic status of patients and individual parameters of antidepressant’s metabolism took into account in every clinical case. Results of this research can allowed to forecast effectivene ss, compliance and tolerance of antidepressants.

Keywords

• психогенетика
• психофармакология
• депрессия
• аффективные расстройства