Haematologica (Nov 2017)
Clinical risks and healthcare utilization of hematopoietic cell transplantation for sickle cell disease in the USA using merged databases
- Staci D. Arnold,
- Ruta Brazauskas,
- Naya He,
- Yimei Li,
- Richard Aplenc,
- Zhezhen Jin,
- Matt Hall,
- Yoshiko Atsuta,
- Jignesh Dalal,
- Theresa Hahn,
- Nandita Khera,
- Carmem Bonfim,
- Navneet S. Majhail,
- Miguel Angel Diaz,
- Cesar O. Freytes,
- William A. Wood,
- Bipin N. Savani,
- Rammurti T. Kamble,
- Susan Parsons,
- Ibrahim Ahmed,
- Keith Sullivan,
- Sara Beattie,
- Christopher Dandoy,
- Reinhold Munker,
- Susana Marino,
- Menachem Bitan,
- Hisham Abdel-Azim,
- Mahmoud Aljurf,
- Richard F. Olsson,
- Sarita Joshi,
- Dave Buchbinder,
- Michael J. Eckrich,
- Shahrukh Hashmi,
- Hillard Lazarus,
- David I. Marks,
- Amir Steinberg,
- Ayman Saad,
- Usama Gergis,
- Lakshmanan Krishnamurti,
- Allistair Abraham,
- Hemalatha G. Rangarajan,
- Mark Walters,
- Joseph Lipscomb,
- Wael Saber,
- Prakash Satwani
Affiliations
- Staci D. Arnold
- Emory University Hospital, Atlanta, GA, USA
- Ruta Brazauskas
- CIBMTR (Center for International Blood and Marrow Transplant Research), Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA;Division of Biostatistics, Institute for Health and Society, Medical College of Wisconsin, Milwaukee, WI, USA
- Naya He
- CIBMTR (Center for International Blood and Marrow Transplant Research), Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA
- Yimei Li
- University of Pennsylvania, Philadelphia, PA, USA
- Richard Aplenc
- University of Pennsylvania, Philadelphia, PA, USA
- Zhezhen Jin
- Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY, USA
- Matt Hall
- Division of Pediatric Hematology, Oncology and Stem Cell Transplantation, Department of Pediatrics, Columbia University Medical Center, New York, NY, USA
- Yoshiko Atsuta
- Japanese Data Center for Hematopoietic Cell Transplantation, Nagoya, Japan;Nagoya University Graduate School of Medicine, Japan
- Jignesh Dalal
- Rainbow Babies & Children’s Hospital, Cleveland, OH, USA
- Theresa Hahn
- Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY, USA
- Nandita Khera
- Department of Hematology/Oncology, Mayo Clinic, Phoenix, AZ, USA
- Carmem Bonfim
- Hospital de Clinicas-Federal University of Parana, Curitiba, Brazil
- Navneet S. Majhail
- Blood & Marrow Transplant Program, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH, USA
- Miguel Angel Diaz
- Department of Hematology/Oncology, Hospital Infantil Universitario Nino Jesus, Madrid, Spain
- Cesar O. Freytes
- Texas Transplant Institute, San Antonio, TX, USA
- William A. Wood
- Division of Hematology/Oncology, Department of Medicine, University of North Carolina, Chapel Hill, NC, USA
- Bipin N. Savani
- Division of Hematology/Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
- Rammurti T. Kamble
- Divsion of Hematology and Oncology, Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX, USA
- Susan Parsons
- Tufts Medical Center, Boston, MA, USA
- Ibrahim Ahmed
- Rainbow Babies & Children’s Hospital, Cleveland, OH, USA
- Keith Sullivan
- Duke University Medical Center, Durham, NC, USA
- Sara Beattie
- University of Ottawa, Canada
- Christopher Dandoy
- Cincinnati Children’s Hospital Medical Center, OH, USA
- Reinhold Munker
- Section of Hematology/Oncology, Department of Internal Medicine, Louisiana State University Health Shreveport, LA, USA
- Susana Marino
- University of Chicago Hospitals, Chicago, IL, USA
- Menachem Bitan
- Department of Pediatric Hematology/Oncology, Tel-Aviv Sourasky Medical Center, Israel
- Hisham Abdel-Azim
- Division of Hematology, Oncology and Blood & Marrow Transplantation, Children’s Hospital of Los Angeles, University of Southern California Keck School of Medicine, CA, USA
- Mahmoud Aljurf
- Department of Oncology, King Faisal Specialist Hospital Center & Research, Riydah, Saudi Arabia
- Richard F. Olsson
- Division of Therapeutic Immunology, Department of Laboratory Medicine, Karolinksa Institutet, Stockholm, Sweden;Centre for Clinical Research Sormland, Uppsala University, Sweden
- Sarita Joshi
- Pediatric Hematology, Oncology and BMT, Nationwide Children’s Hospital and Ohio State University Wexner, Columbus, OH, USA
- Dave Buchbinder
- Division of Pediatrics Hematology, Children’s Hospital of Orange County, Orange, CA, USA
- Michael J. Eckrich
- Levine Children’s Hospital, Charlotte, NC, USA
- Shahrukh Hashmi
- Department of Oncology, King Faisal Specialist Hospital Center & Research, Riydah, Saudi Arabia;Department of Internal Medicine, Mayo Clinic, Minneapolis, MN, USA
- Hillard Lazarus
- Seidman Cancer Center, University Hospitals Case Medical Center, Cleveland, OH, USA
- David I. Marks
- Adult Bone Marrow Transplant, University Hospitals Bristol NHS Trust, Bristol, United Kingdom
- Amir Steinberg
- Department of Hematology-Oncology, Mount Saini Hospital, New York, NY, USA
- Ayman Saad
- Division of Hematology/Oncology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA
- Usama Gergis
- Hematologic Malignancies & Bone Marrow Transplant, Department of Medical Oncology, New York Presbyterian Hospital/Weill Cornell Medical College, New York, NY, USA
- Lakshmanan Krishnamurti
- Emory University Hospital, Atlanta, GA, USA
- Allistair Abraham
- Division of Blood and Marrow Transplantation, Center for Cancer and Blood Disorders, Children’s National Medical Center, Washington, DC, USA
- Hemalatha G. Rangarajan
- Pediatric Hematology, Oncology and BMT, Nationwide Children’s Hospital and Ohio State University Wexner, Columbus, OH, USA
- Mark Walters
- Children’s Hospital & Research Center Oakland, Oakland, NY, USA
- Joseph Lipscomb
- Health Policy and Management, Rollins School of Public Health, Winship Cancer Institute, Emory University, Atlanta, GA, USA
- Wael Saber
- CIBMTR (Center for International Blood and Marrow Transplant Research), Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA
- Prakash Satwani
- Division of Pediatric Hematology, Oncology and Stem Cell Transplantation, Department of Pediatrics, Columbia University Medical Center, New York, NY, USA
- DOI
- https://doi.org/10.3324/haematol.2017.169581
- Journal volume & issue
-
Vol. 102,
no. 11
Abstract
Advances in allogeneic hematopoietic cell transplantation for sickle cell disease have improved outcomes, but there is limited analysis of healthcare utilization in this setting. We hypothesized that, compared to late transplantation, early transplantation (at age
