Microbiological, Clinical and Radiological Aspects of Diabetic Foot Ulcers Infected with Methicillin-Resistant and -Sensitive <i>Staphylococcus aureus</i>

Abstract

Diabetic foot ulcer (DFU) is one of the most common chronic complications of diabetes. This study aimed to assess the factors with an impact on the infection of diabetic foot ulcers by methicillin-resistant S. aureus and to evaluate the influence of methicillin resistance on the frequency of osteitis (based on classic X-ray images). A total of 863 patients suffering from DFU were analyzed during the study period. Out of 201 isolated S. aureus cases, 31 (15.4%) were methicillin-resistant (MRSA). MRSA infections were associated with a higher incidence of osteitis compared to MSSA infections (p 50%) inflammatory bone changes (p p p p Pseudomonas sp. and other non-fermenting bacilli than those infected with MSSA (p S. aureus should be closely monitored in the course of using antibiotics and treated with narrow-spectrum antibiotics.

Keywords

• diabetes
• <i>Staphylococcus aureus</i>
• methicillin resistance
• MRSA
• diabetic foot
• DFU