Evaluation of a Direct, Rapid Immunohistochemical Test for Rabies Diagnosis

Abstract

A direct rapid immunohistochemical test (dRIT) was evaluated under field and laboratory conditions to detect rabies virus antigen in frozen and glycerol-preserved field brain samples from northwestern Tanzania. Compared to the direct fluorescent antibody test, the traditional standard in rabies diagnosis, the dRIT was 100% sensitive and specific.

Keywords

• rabies
• diagnosis
• immunohistochemistry
• dispatch
• Tanzania