Nature Communications (Mar 2023)
Evolutionary conservation of the fidelity of transcription
- Claire Chung,
- Bert M. Verheijen,
- Zoe Navapanich,
- Eric G. McGann,
- Sarah Shemtov,
- Guan-Ju Lai,
- Payal Arora,
- Atif Towheed,
- Suraiya Haroon,
- Agnes Holczbauer,
- Sharon Chang,
- Zarko Manojlovic,
- Stephen Simpson,
- Kelley W. Thomas,
- Craig Kaplan,
- Peter van Hasselt,
- Marc Timmers,
- Dorothy Erie,
- Lin Chen,
- Jean-Franćois Gout,
- Marc Vermulst
Affiliations
- Claire Chung
- School of Gerontology, University of Southern California
- Bert M. Verheijen
- School of Gerontology, University of Southern California
- Zoe Navapanich
- School of Gerontology, University of Southern California
- Eric G. McGann
- School of Gerontology, University of Southern California
- Sarah Shemtov
- School of Gerontology, University of Southern California
- Guan-Ju Lai
- School of Gerontology, University of Southern California
- Payal Arora
- Department of Biological Sciences, University of Pittsburgh
- Atif Towheed
- Children’s hospital of Philadelphia, Center for Mitochondrial and Epigenomic Medicine
- Suraiya Haroon
- Children’s hospital of Philadelphia, Center for Mitochondrial and Epigenomic Medicine
- Agnes Holczbauer
- Children’s hospital of Philadelphia, Center for Mitochondrial and Epigenomic Medicine
- Sharon Chang
- Keck School of Medicine, University of Southern California
- Zarko Manojlovic
- Keck School of Medicine, University of Southern California
- Stephen Simpson
- College of Life Sciences and Agriculture, University of New Hampshire
- Kelley W. Thomas
- College of Life Sciences and Agriculture, University of New Hampshire
- Craig Kaplan
- Department of Biological Sciences, University of Pittsburgh
- Peter van Hasselt
- Department of Metabolic Disease, University of Utrecht
- Marc Timmers
- Department of Urology, Medical Center - University of Freiburg
- Dorothy Erie
- Department of Chemistry, University of North Carolina
- Lin Chen
- Department of Molecular and Cellular Biology, University of Southern California
- Jean-Franćois Gout
- Department of Biological Sciences, Mississippi State University
- Marc Vermulst
- School of Gerontology, University of Southern California
- DOI
- https://doi.org/10.1038/s41467-023-36525-w
- Journal volume & issue
-
Vol. 14,
no. 1
pp. 1 – 15
Abstract
The molecular mechanisms that ensure faithful transcription of genetic information are still unclear. Chung et al. identify various genes, alleles and processes that affect the fidelity of transcription multiple organisms, suggesting evolutionary conservation of fidelity factors, and compare the error rate of transcription among these species.
