Hypothermia effects on liver and kidney oxidative stress parameters in an experimental model of sepsis in rats

Abstract

Oxidative stress (OS) seems to be an important mediator of cellular injury, from which sepsis can proceed. Studies have demonstrated the protective effect of controlled hypothermia in sepsis. This study aimed to evaluate its effects on OS parameters in rat hepatic and renal tissue septic after caecal ligation and puncture (CLP).

Keywords

• rats
• hypothermia
• sepsis
• oxidative stress