Case report: Candida blankii osteo-articular infection in a patient with Chronic Granulomatous Disease

Abstract

Candida blankii is a recently reported yeast causing rare cases of fungemia. This species presents high minimum inhibitory concentrations (MICs) to fluconazole and echinocandins. We report an atypical C. blankii metacarpophalangeal osteo-articular infection in a patient with Chronic Granulomatous Disease. The patient was initially treated by a combination of voriconazole and 5-fluorocytosine (5-FC). However, the treatment was subsequently changed to posaconazole and then to a combination of caspofungin and 5-FC.2012 Elsevier Ltd. All rights reserved.

Keywords

• Candida blankii
• Chronic Granulomatous Disease
• Osteoarticular infection
• Emerging pathogen