Navigating diagnostic challenges in xanthogranulomatous cholecystitis: A case report

Ongden Yonjen Tamang, MD; Prajwal Dahal, MD; Santosh Maharjan, MD; Govinda Adhikari, MD; Rudra Prasad Upadhyaya, MD; Sabina Parajuli, MBBS; Natasha Dhakal, MBBS

Radiology Case Reports (Dec 2024)

Navigating diagnostic challenges in xanthogranulomatous cholecystitis: A case report

Ongden Yonjen Tamang, MD,
Prajwal Dahal, MD,
Santosh Maharjan, MD,
Govinda Adhikari, MD,
Rudra Prasad Upadhyaya, MD,
Sabina Parajuli, MBBS,
Natasha Dhakal, MBBS

Affiliations

Ongden Yonjen Tamang, MD: Department of Radiology and Imaging, Grande International Hospital, Kathmandu, Nepal
Prajwal Dahal, MD: Department of Radiology and Imaging, Grande International Hospital, Kathmandu, Nepal; Corresponding author.
Santosh Maharjan, MD: Department of Radiology and Imaging, Grande International Hospital, Kathmandu, Nepal
Govinda Adhikari, MD: Department of Radiology and Imaging, Grande International Hospital, Kathmandu, Nepal
Rudra Prasad Upadhyaya, MD: Department of Radiology and Imaging, Grande International Hospital, Kathmandu, Nepal
Sabina Parajuli, MBBS: Department of Pathology, Bir Hospital, Kathmandu, Nepal
Natasha Dhakal, MBBS: Department of Cardiothoracic and Vascular Surgery, Manmohan Cardiothoracic Vascular and Transplant Center, Institute of Medicine, Tribhuvan University, Kathmandu, Nepal

Journal volume & issue: Vol. 19, no. 12
pp. 5674 – 5677

Abstract

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Xanthogranulomatous cholecystitis (XGC) presents a diagnostic challenge due to its rarity and varied clinical manifestations and nonspecific radiological findings. We here describe a 67-year-old man with right hypochondriac pain, where imaging revealed irregular thickening of the gallbladder wall, prompting consideration of various differential diagnoses including gallbladder malignancy, adenomyomatosis, and complicated cholecystitis. With inconclusive lab results, cholecystectomy with potential extended hepatectomy was advised. Intraoperatively, an inflamed gallbladder was observed. Histopathological examination confirmed XGC, stressing histological verification. Complete cholecystectomy is standard, with partial resection an option. Our case details the complexity in diagnosis and management of XGC.

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://www.sciencedirect.com/journal/radiology-case-reports

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