Experience with ceftazidime–avibactam treatment in a tertiary care center in Saudi Arabia

Abstract

Introduction: Carbapenem-resistant organisms have become major healthcare-associated pathogens and are responsible for significant morbidity and mortality worldwide. Cases and managements: This case-series describes our experience with ceftazidime–avibactam in the treatment of six cases with carbapenem-resistant organisms in King Abdulaziz Medical City in Riyadh, Saudi Arabia. After trying various combinations of antibiotic therapies without improvement, cases were treated with ceftazidime–avibactam. Outcomes: Five of the six achieved complete cure, both clinically and microbiologically. Keywords: MDR-infections, Ceftazidime–avibactam, Saudi Arabia