Frontiers in Cardiovascular Medicine (Jun 2021)

COVID-19 and Cardiomyopathy: A Systematic Review

  • Fatemeh Omidi,
  • Bahareh Hajikhani,
  • Seyyedeh Neda Kazemi,
  • Ardeshir Tajbakhsh,
  • Sajedeh Riazi,
  • Mehdi Mirsaeidi,
  • Ali Ansari,
  • Masoud Ghanbari Boroujeni,
  • Farima Khalili,
  • Sara Hadadi,
  • Mohammad Javad Nasiri

DOI
https://doi.org/10.3389/fcvm.2021.695206
Journal volume & issue
Vol. 8

Abstract

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Background: Cardiomyopathies (CMPs) due to myocytes involvement are among the leading causes of sudden adolescent death and heart failure. During the COVID-19 pandemic, there are limited data available on cardiac complications in patients with COVID-19, leading to severe outcomes.Methods: We conducted a systematic search in Pubmed/Medline, Web of Science, and Embase databases up to August 2020, for all relevant studies about COVID-19 and CMPs.Results: A total of 29 articles with a total number of 1460 patients were included. Hypertension, diabetes, obesity, hyperlipidemia, and ischemic heart disease were the most reported comorbidities among patients with COVID-19 and cardiomyopathy. In the laboratory findings, 21.47% of patients had increased levels of troponin. Raised D-dimer levels were also reported in all of the patients. Echocardiographic results revealed mild, moderate, and severe Left Ventricular (LV) dysfunction present in 17.13, 11.87, and 10% of patients, respectively.Conclusions: Cardiac injury and CMPs were common conditions in patients with COVID-19. Therefore, it is suggested that cardiac damage be considered in managing patients with COVID-19.

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